Journal of Neonatal Biology

Sickle Cell Disease Center, Howard University Washington, DC, USA

Publications

• Research   
  Routine Screening for Sickle Cell Disease during Pregnancy: Epidemiological and Haemoglobin Profile in Congo
  Author(s): Alexis Elira Dokekias, Josué Simo Louokdom*, Letso Thibaut Ocko Gokaba, Firmine Olivia Galiba Atipo Tsiba Gokaba, Jayne Chelsea Bango, Lydie Ngolet Ocini, Clatere Itoua and James Taylor
  
  Sickle-cell disease, a genetic condition with a high prevalence in sub-Saharan Africa, is transmitted in an autosomal recessive mode. Its screening during pregnancy makes it possible to identify carriers of the S gene which constitute a risk for the unborn child. In order to promote the use of immuno-chromatographic tests, we have set ourselves the task of establishing the epidemiological profile and determining the Emmel test performance. Analytical cross-sectional study of three months duration carried out in the 12 departments of Congo in pregnant women, from 12 weeks of amenorrhea, Admitted for Antenatal Consultation (ANC). The studied variables were epidemiological, Emmel test and immuno-chromatographic profile of haemoglobin. 782 pregnant women screened, of which 27.88% were AS sickle cell trait and 1.79% homozygous SS. The median age of sickle .. View more»
  

  DOI: 10.35248/2167-0897.22.11.335

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