Charles Myers

Department of Oncology, Foundation for Cancer Research and Education, Earlysville, Virginia, USA

Publications
  • Research Article   
    Impact of Dutasteride on PSA Kinetics and Time to Progression in Men with PSA-only Recurrent Prostate Cancer
    Author(s): Charles Myers*

    Background: AVODART After Radical Therapy For Prostate Cancer Study (ARTS) reported dutasteride reduced PSA Doubling (PSADT) at two years by 66% and disease progression by 59%. The durability of the cancer control is unknown. Objective: Explore the impact of dutasteride on PSADT and time to progression in men with PSA-only recurrent disease. Design, Setting and Participants: Retrospective examination of the impact of dutasteride on PSA kinetics and time to progression with PSA-only recurrent prostate cancer. Intervention: Dutasteride daily. Outcome, measurement and statistical analysis: Change in PSA over time was determined by linear regression of natural log of PSA versus time. The slope of that curve was used as a measure of exponential PSA progression. Impact of dutasteri.. View more»

    DOI: 10.35248/2157-2518.21.s19.001

    Abstract HTML PDF