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Chan Ka Yan Gloria
Department of Medicine, Tseung Kwan O Hospital, Hong Kong, China
Publications
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Research Article
A Retrospective Study into Etiology, Clinical Outcomes and Prognostic Factors of Severe Acute Liver Injury in Hong Kong
Author(s): Chan Ka Yan Gloria* and Tsang Woon Choy Steven
Background: Severe Acute Liver Injury (ALI) contributes to significant morbidity and mortality in hospitalized patients. Early recognition, identification and treatment of the underlying cause are necessary for better outcome. This study aimed to investigate the common causes of severe elevation of Alanine Aminotransferase (ALT) in Chinese patients admitted to hospital in Hong Kong, and also to determine the clinical outcomes and prognostic factors associated with the ALI. Methods: This was a retrospective, single center cohort study conducted in a regional hospital between January 2017 and December 2019. Patients’ data admitted with ALT ≥ 1000 U/L were retrieved from the Department of Pathology data base. Their baseline clinical demographics, laboratory profiles and the etiology of ALI were analyzed. The primary .. View more»