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Carmine H
Department of Thrombosis and Vascular Diseases Laboratory, RMIT University, Bundoora, Victoria, Australia
Publications
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Research Article
Relative Risk of Haemolytic Disease of the Foetus and New-born Based on Maternal Alloantibody Specificity: Systematic Review and MetaAnalysis
Author(s): Carmine H and Denise E. Jackson
Haemolytic Disease of the Foetus and Newborn (HDFN) is a common cause of foetal morbidity involving the incompatibility of alloimmunised maternal erythrocyte IgG antibodies and foetal erythrocytes causing haemolysis in the neonate. HDFN severity will depend upon the maternal erythrocyte antibody specificity and the antibody titre strength of the antibody. The primary aim of this review is to determine what is the relative risk of neonatal hyperbilirubinaemia and anaemia when comparing different erythrocyte antibody specificities present in pregnant mothers known to cause haemolytic disease of the foetus and newborn? To obtain appropriate papers to be used in this study, Scopus, Pubmed and Embase databases employed using the search dates from January 1st 2012 until August 31st 2022 using a range of keywords. Meta-analysis was conducted on these papers using Openmet.. View more»