Department of Paediatrics and Child Health, University College Cork, Cork, Ireland
Research Article
Examining the Use and Outcomes of Peanut Oral Immunotherapy in Peanut-Allergic Children: A Systematic Review of the Literature
Author(s): Camille Mutukistna, Caoimhe Cronin, Kevin Sheridan, Ciara Tobinb and Juan Trujillo Wurttele*
Peanut allergy is one of the most common allergies in children, affecting 1% to 4.5% of the population with
a rise in prevalence over the past decade. It is a major public health concern as it significantly diminishes the
quality of life of those who are allergic, their families and their caregivers. Peanut allergy is an IgE-mediated
Type I hypersensitivity response to peanuts and Peanut Oral Immunotherapy (P-OIT) is a treatment which
attempts to mediate this over reactive response to peanuts by repeating and increasing administration of
peanut protein doses.
The specific objectives of this review are as follows:
1. To characterize the dosing regimens used for P-OIT in peanut-allergic children.
2. To examine the efficacy and effectiveness of P-OIT in peanut-allergic children.
3. To assess treatment experience of patients during P-OIT in p.. View more»