Department of Medical Psychology, luliu Hațieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania
Andrei Buciuta was from the department of cell and molecular biology of Iuliu Ha?ieganu University of Medicine and Pharmacy. the University is located at Cluj-Napoca of country Romania
Review Article
Antidepressant Treatment for Depression in Alzheimer’s Dementia: Systematic Review Article
Author(s): Buciuta A, Vinasi RC and Coman HG*
Introduction: Alzheimer's Dementia (AD) is a neurodegenerative disease characterized by progressive cognitive
decline. Neuropsychiatric symptoms (NPS) are frequently described in AD. Among the non-cognitive symptoms that
can occur in AD, depression is the most common one.
Objective: The aim was to review published studies in order to examine the efficacy and safety of antidepressant
medication for depression in AD.
Methods: An electronic database search was performed using the keywords: ” antidepressant ” , “ randomized
controlled trial (RCT)”, “depression”, “dementia”, ”Alzheimer’s disease”. For the evaluation of efficacy, the reduction
of scores on the evaluation scales of depression and the rate of response or remission were used and fo.. View more»