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Brigitte Banjac
Department of Laboratory Medicine, School of Health and Biomedical Sciences, RMIT University, Bundoora, Victoria, Australia
Publications
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Research Article
The Impact of LTOWB vs. Standard Component Therapy on TransfusionRelated Complications in Trauma Resuscitation: A Systematic Review and Meta-Analysis
Author(s): Brigitte Banjac and Denise E. Jackson*
Background: Haemorrhage secondary to trauma is the leading cause of preventable fatalities. Low Titre O Whole Blood (LTOWB) has been reintroduced as a significant alternative to Component Therapy (CT), in trauma resuscitation due to its balanced composition. This systematic review and meta-analysis compares the incidence of transfusion related complications, including Pulmonary Embolism (PE), Deep Vein Thrombosis (DVT), Acute Kidney Injury (AKI) and Acute Respiratory Distress Syndrome (ARDS), in trauma patients receiving LTOWB versus CT. Methods: A search of PubMed, Scopus, Embase and Web of Science databases was conducted to identify studies reporting adverse outcomes in adult civilian trauma patients receiving LTOWB or CT. Eligible studies were assessed for quality using the STROBE checklist. Meta-analyses were performed .. View more»