Department of Health Affairs, Ahad rofidah General Hospital, Abha, Saudi Arabia
Review Article
The Biological Structure of Platelet and their Role with Subpopulations in
Haemostasis
Author(s): Fahad SM Alshehri*, Salem SS Alqahtani and Anwar MS Alraizah
Platelets are the smallest blood cells which circulated in the blood in inactive status. It is activated during the blood
vessel injury to stop the bleeding through formation of platelet plug. It is also enhance the coagulation pathway by
expose of Phosphatidylserine (PS) to increase the generation of thrombin and thereby increase the activation of
other platelets. The unique structure of platelets supports them to do multifunction in different aspects. There are a
different platelet populations based on their functions and their ages. In this review we aim to write overview of
platelets including the structure, receptors, functions in adhesion and aggregation and identify the platelet subtypes
and their role in haemostasis and thrombosis. .. View more»