Department of Neurology, Alpha Medica Stem Clinic, Targoviste, Romania
Research Article
Percutaneous Application of Adipose Derived Stem Cells (ADSCs) in Non-Union of Long Bone Fractures
Author(s): Himanshu Bansal*, Jerry Leon, Anupama Bansal and Iustin Preoteasa
Aim: Non-union is a common clinical complication that causes serious limb debilities and eventually leads to
permanent limb impairment if not treated timely. Each bone fracture is unique and no common treatment modality
will prove efficacious. To date, stem cells derived from bone marrow tissue are used for the treatment of non-union
fractures. Present study reported personalized stem-cell therapy with Adipose tissue Derived Stem Cells (ADSCs)/
Stromal Vascular Fraction (SVF) in seven patients with history of non-union of long bones.
Methods: A total of 11 patients were enrolled for the study and 7 patients could be followed up for the treatment.
ADSCs/SVF cells were extracted from adipose tissues and re-suspended in peripheral blood Plasma Rich in Platelets
(PRP). The preparation was injected into the non-union site aided by.. View more»