Department of Partner Relations and Medical Affairs, University of TOP Pharma Pharmacy Witikon, Zurich, Switzerland
Research Article
Prevalence of Drug-Drug Interactions and Duplicate Therapy in Chronic Patients in Switzerland: A Real-World Data Study
Author(s): Redona Hafizi* and Anja Bauert
The primary purpose of this study was to determine the prevalence of Drug-Drug Interaction (DDI) and duplicate
therapy in chronic patients in a completely random study population engaged in digital health apps in Switzerland.
In this cross-sectional study, polypharmacy checks for 100 completely anonymous patients were analyzed for the
occurrence of DDIs and duplicate therapy. Logistic regression models were used to identify factors associated with
DDIs and duplicate therapy. DDIs and duplicate therapy prevalence were 34% and 33%, respectively. Chi-Square
test discovered a significant association between the DDIs and duplicate therapy variables. Logistic regression models
showed a strong association between the number of medications taken and higher odds of DDIs occurring in our
population only. In conclusion, our study shows that polypharmacy is a determining fact.. View more»