Satsang Herbal Research Laboratory, Satsang, Deoghar, Jharkhand, India
Ajit Kar recipient of many awards and grants for his valuable contributions and discoveries in major area of subject research in Satsang Herbal Research and Analytical Laboratories. His international experience includes various programs, contributions and participation in different countries for diverse fields of study. His research interests reflect in his wide range of publications in various national and international journals.
Research
Establishing a Remedy for Phenylketonuria Disease from Indian Ayurvedic Herbs
Author(s): Preenon Bagchi*, SophieVisvikis-Sieste and Ajit Kar
The phenylketonuria (PKU) disease is an inherited disorder that increases the levels of a substance called phenylalanine in the blood and if not treated, phenylalanine can build up to harmful levels in the body. People with this disorder can't break down the amino acid phenylalanine. This phenylalanine, then builds up in the blood and brain causing intellectual disability and other serious health problems. It is rare but a serious inherited disorder. The main objective of this study is to establish a remedy for the phenylketonuria disease (novel drug leads for phenylketonuria disease’s receptors viz. ASCL1 gene (achaete-scute family bHLH transcription factor 1), GCH1 gene (GTP cyclohydrolase 1) and MAOB (Monoamine Oxidase B)) using phytocompounds from ayurvedic herbs. To achieve this objective we performed virtual screening with phytocompounds from ayurvedic herbs against th.. View more»