Journal of Tumour Research & Reports

Department of Hematology, Iran University of Medical Sciences, Tehran, Iran

Publications

• Short Communication   
  Study of hematopoietic microenvironment in some blood disorders particularly in malignant hematopoietic diseases
  Author(s): Ahmad Reza Rahnemoon*
  
  Hematopoietic neoplasms are known or assumed to be clonal processes arising as the result of genetic errors. But I think some other items should be involved in these neoplasms too. As we know, hematopoietic stem cells (HSCs) are classified as important stem cells due to their ability to differentiate to the cells including the lineages of lymphoid and myeloid cells. Lymphoid cell lineage includes T and B cells while granulocytes, monocytes, erythrocytes, megakaryocytes belong to the lineage of myeloid. Hematopoiesis, is controlled by several complex interactions between genetic processes in blood progenitor cells and bone marrow microenvironment as an important regulator in this matter. Thus, we must understand how malignancy disrupts the normal mechanisms of hematopoiesis which controlling HS.. View more»
  

  Abstract PDF