General Directorate of Health Affairs in “Aseer” Region, Regional Laboratory and Central Blood Bank, Abha, Saudi Arabia
Research Article
Identification of Occult Hepatitis B Infection (OBI) among Blood Donors at Aseer Southern Region in Saudi Arabia
Author(s): Asra Khanum MD, Ahmad M Alamri PhD, Abdurrahman M Alshehri, Abdulaziz S Alsabrah, Mohammed S Alshehri, Galib M Albahja and Fahad S Alshehri PhD*
Background: Hepatitis B infection (HBV) and other transfusion-transmitted viruses remain a major concern in transfusion medicine. Blood transfusions can spread Occult HBV Infection (OBI), but the prevalence is limited. OBIs in donors have been obvious after blood transfusion organizations began using sensitive HBV Deoxyribonucleic acid (DNA) Nucleic Acid Amplification Technique (NAT) screening. Residual risk assessments may not accurately predict transfusion-related OBI infection rates. Several nations now use HBV DNA confirmatory Nucleic Acid Tests (NATs).
Materials and methods: In this study, we screened blood donors in the “Aseer” Province of Saudi Arabia for HBV DNA, anti-HBc, and HBV surface Antigen (HBsAg) to determine the prevalence and annual trends of OBI infection. The present study was conducted from January .. View more»