PMC/PubMed Indexed Articles
Indexed In
- Academic Journals Database
- Open J Gate
- Genamics JournalSeek
- JournalTOCs
- China National Knowledge Infrastructure (CNKI)
- Scimago
- Ulrich's Periodicals Directory
- RefSeek
- Hamdard University
- EBSCO A-Z
- OCLC- WorldCat
- Publons
- MIAR
- University Grants Commission
- Geneva Foundation for Medical Education and Research
- Euro Pub
- Google Scholar
Useful Links
Share This Page
Open Access Journals
- Agri and Aquaculture
- Biochemistry
- Bioinformatics & Systems Biology
- Business & Management
- Chemistry
- Clinical Sciences
- Engineering
- Food & Nutrition
- General Science
- Genetics & Molecular Biology
- Immunology & Microbiology
- Medical Sciences
- Neuroscience & Psychology
- Nursing & Health Care
- Pharmaceutical Sciences
Abstract
Group B Streptococcal Colonization and Intrapartum Antibiotics: Why a Vaccine is Urgently Needed
The importance of global group B streptococcal (GBS) colonization during pregnancy is briefly reviewed in this short article. About 20% all pregnant women worldwide are colonized with this organism necessitating the use of intrapartum antibiotic prophylaxis (IAP) in order to prevent neonatal GBS disease. In some geographic regions rates of colonization are as high as 35%. Such a high rate of IAP is shown to be concerning because of childhood adverse effects. We briefly summarize 5 main childhood adverse outcomes from IAP which include antibiotic resistance, the development of various atopic diseases, dysbyosis, obesity, and impaired immune function. Finally, the article clearly lists 4 reasons why a GBS vaccine is specifically urgently needed in order to curb the often unnecessary if not dangerous use of IAP to prevent against the onset of neonatal GBS disease. It is hoped that such a vaccine could reduce the rate of IAP from a high of 40% to a low of 10%.
Published Date: 2020-10-30; Received Date: 2020-10-08