Journal of Nanomedicine & Nanotechnology

Abstract

Gene Delivery Systems: Using Nanoparticles to Deliver DNA/RNA for Genetic Resistance in Plants

Taito Nakashima*

Nanoparticle-mediated gene delivery offers a groundbreaking approach to enhancing plant resistance against diseases, addressing the limitations of traditional agricultural practices. This article explores the mechanisms and benefits of using nanoparticles as carriers for DNA and RNA, facilitating genetic modifications that confer resistance to various pathogens. Key synthesis components include metallic nanoparticles (e.g., gold, silver), polymeric nanoparticles (e.g., chitosan), and lipid-based nanoparticles (e.g., liposomes), each providing unique advantages in protecting and delivering genetic material. The process involves nanoparticle synthesis, genetic material loading, targeted delivery, and subsequent gene expression. Benefits include targeted delivery, protection of genetic material, reduced dosages, and enhanced uptake by plant cells. Despite challenges related to biosafety, delivery efficiency, regulatory approval, and cost-effectiveness, nanoparticle-mediated gene delivery holds significant promise for revolutionizing modern agriculture. This technology aims to develop resilient crop varieties, ensuring food security and sustainability amid global challenges.

Published Date: 2024-05-31; Received Date: 2024-05-01