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Taito Nakashima
Department of Stem Cell Biology and Medicine, Graduate School of Medical Sciences, Kyushu University, Japan
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Case Report
Gene Delivery Systems: Using Nanoparticles to Deliver DNA/RNA for Genetic Resistance in Plants
Author(s): Taito Nakashima*
Nanoparticle-mediated gene delivery offers a groundbreaking approach to enhancing plant resistance against diseases, addressing the limitations of traditional agricultural practices. This article explores the mechanisms and benefits of using nanoparticles as carriers for DNA and RNA, facilitating genetic modifications that confer resistance to various pathogens. Key synthesis components include metallic nanoparticles (e.g., gold, silver), polymeric nanoparticles (e.g., chitosan), and lipid-based nanoparticles (e.g., liposomes), each providing unique advantages in protecting and delivering genetic material. The process involves nanoparticle synthesis, genetic material loading, targeted delivery, and subsequent gene expression. Benefits include targeted delivery, protection of genetic material, reduced dosages, and enhanced uptake by plant cells. Despite challenges related to biosafety,.. View more»