Insang Lee
Divine Lab Co Ltd, South Korea
Keynote: Pharm Anal Acta
Water has been considered as matrix of the world and of all its creatures. Some unusual and significant properties are involved in water such as its physical properties, chemical properties, solvent potency, hydrogen bonds forming ability and amphoteric natures. Biologists proved that water is the backdrop on which life’s molecular components are designed. The same applies to our finding that hydronium ions (H3O+) seem to have a better option for the water surface. H3O+ may form three donor hydrogen bonds to neighboring water molecules, but because most of the positive charge resides on the oxygen atom, it can no longer act as a good hydrogen bond acceptor. Indeed, this makes the oxygen somewhat hydrophobic, so that H3O+ acts as an amphiphile. In this way, reduced hydrogen bond capacity encourages the surface accumulation of H3O+, oriented with the oxygen atom outermost. As much the same behavior might be expected at hydrophobic surfaces, this finding could have significant implications for biomolecular hydration that have investigated by us; for example, one might expect to see a shift in the dissociation of protonatable residues close to hydrophobic patches and perhaps even a stabilization of hydrophobic species by a kind of surfactant behavior of H3O+. The water molecules solvating a hydronium (H3O+) ion can actually facilitate proton transport by shuttling it to another molecule. In this way, a specific proton does not itself diffuse through the medium; rather, there is a cooperative transfer of protons between successive molecules.
Insang Lee was born in May 13, 1950 and raised in Seoul, Korea and B.S. at college of art of Chungang University in Korea. After that went to USA for sturdy more, B.S. at University of Colorado and MBA at University of Colorado. He worked at State Metal Corp. as Sales Director of non-ferrous metal in USA and Sales Rep. of Kobe Steel of Japan in USA. He set up the factory in Korea for metal working such as brass bed, lighting fixtures and CEO of Tricomex International Corp in California for International trading corp. He set up the lab in Korea for Hydronium sturdy and test since 1998 to present.
E-mail: saupil@hotmail.com