Journal of Neonatal Biology

Use of non-invasive ventilation in reducing partial pressure of Carbon dioxide level (PaCO2) in neonates with Respiratory Distress Syndrome

5^th International Conference on Neonatology and Perinatology

August 24-25, 2022 | Webinar

Rida Ali

Assistant Professor, Pediatrics PNS SHIFA / Bahria University Medical & Dental College, Pakistan

Scientific Tracks Abstracts: J Neonatal Biol

Abstract:

It has been observed that non-invasive ventilation used in premature with Respiratory distress syndrome and notably decrease level of partial pressure of carbon-dioxide (PaCO2) level in blood.The primary goal of this study was to assess the effect of non-invasive ventilation in decreasing the level of partial pressure of carbon dioxide (PaCO2) level and supplementary oxygen need in premature neonates with Respiratory Distress Syndrome STUDY DESIGN AND SETTINGS: This randomized controlled trial was done in Jan 2021 till August 2021 at PNS Shifa Hospital Karachi. METHOD: Neonates with gestational age less than 34 weeks with RDS at birth were randomly assigned to nasal intermittent positive pressure ventilation (NIPPV) and nasal high frequency oscillatory ventilation (NHFOV) for respiratory support after giving surfactant. Twenty three preterm babies were included in each group. Level of partial pressure of carbon dioxide at 2hrs and 24hrs of non-invasive ventilation and supplementary oxygen need was evaluated. RESULTS: Non-invasive ventilation was found to reduce the PaCO2 level (p= .01), NIPPV (43.06±13.74) vs. (33.63±19.99) in NHFOV at 2hrs and 24hrs NIPPV (19.89±7.18) vs. NHFOV (14.04±8.39).Value of pH was also significant in two groups with optimal mean airway pressure. Supplementary oxygen period were also reduced in NHFOV than NIPPV group (35.7% vs. 64.3%). CONCLUSION: NHFOV was a beneficial mode in maintaining level of pH, PaCO2 level and reducing need of supplementary oxygen in preterm babies with RDS.

Biography :

A practicing physician in the field of healthcare in the state of Kerala in India for the last 34 years and very much interested in basic research. My interest is spread across the fever, inflammation and back pain. I am a writer. I already printed and published Ten books on these subjects. I wrote hundreds of articles in various magazines. After scientific studies, we have developed 8000 affirmative cross checking questions. It can explain all queries related to fever.