Journal of Stem Cell Research & Therapy

T-patterns in human and neuronal interactions and on DNA: Spatio-temporal self-similarity and translation symmetry

Annual Summit on Cell Signaling, Cell Therapy and Cancer Therapeutics

September 27-28, 2017 Chicago, USA

Magnus S Magnusson

University of Iceland, Iceland

Keynote: J Stem Cell Res Ther

Abstract:

How do cells organize their interactions in time? As a candidate for the search for answers, this talk considers a particular pattern type, called T-pattern. Originally proposed and developed for ethological analysis of human interaction, it has more recently also been applied to dynamic signaling between cells in neuronal networks in brains. The T-pattern is a selfsimilar hierarchical structure on a single dimension, in time or space, and can be seen as a particular recurrent statistical pseudo-fractal object characterized by statistically significant translation symmetry over all its instances. Just two occurrences may allow detection. A number of extensions to the T-pattern have been defined together constituting the T-System, all of which can be detected using the especially developed THEMETM software widely applied to interaction analysis of organisms from neurons to humans, while DNA and protein analyses are in progress. Examples of T-patterns detected in human interactions and within neuronal networks are presented. The T-pattern structure of genes in DNA and, consequently, in proteins, suggests self-similar spatio-temporal structure across wide spans of temporal and spatial scales, from nano, to neuronal, to human. The self-similarity extends to broader aspects of intra- and inter-cellular interactions as the organization of the biologically recent human mass-societies seem to reflect important aspects of social organization in Cell City as will also be exemplified.

Biography :

Magnus S Magnusson, PhD, Research Professor, created the T-pattern model with detection algorithms and special purpose software (THEMETM, PatternVision). He Co-directed a two-year DNA analysis project, published numerous papers and invited talks and keynotes at international conferences and at leading universities in Europe, Japan and the US within Ethology, Science of Religion, Mathematical Sciences, Neuroscience, Bioinformatics, Genetics, Proteomics and Mass Spectroscopy. He served as Deputy Director 1983-1988 in the Museum of Mankind of the National Museum of Natural History, Paris. From 1988 to 1993, he served as invited Professor at the University of Paris (V, VIII & XIII) in Psychology and Ethology (Biology of Behavior). Since 1991, he is the Founder and Director of the Human Behavior Laboratory, University of Iceland, leading a formalized network of 24 universities initiated at the University of Paris V, Sorbonne, Paris, in 1995 based on “Magnusson’s analytical model”.