Journal of Aquaculture Research & Development

The distribution and elimination of Norfloxacin in Chinese white shrimp (Fenneropenaeus chinensis) aquaculture system

International Conference on Aquaculture & Fisheries

July 20-22, 2015 Brisbane, Australia

Zhi-Qiang Chang, Ming Sun, Qian-Qian Zhai and Jian Li

Posters-Accepted Abstracts: J Aquac Res Development

Abstract:

The Chinese white shrimp Fenneropenaeus chinensis is one of the most valuable aquatic shrimp resources in China, distributed mainly in the Bohai Sea and the Yellow Sea. It has also been of great importance to the mariculture industry in China due to the good taste, high commercial value and adaptation to artificial culture conditions. The production used to reach over 200,000 tons in 1989-1992 then devastated significantly by a series of epidemics in the 1990s and early 2000s and maintained around 45,000 tons recently. Antibiotics such as Norfloxacin (NFLX) were occasionally used during shrimp aquaculture to control bacterial infections caused by Vibrio anguillarum or other marine pathogens. Therefore, in the study we investigated the distribution and elimination of norfloxacin in F. chinensis at different developmental stages and in culture environment as well. First, the mature parent shrimp were exposed to NFLX through medicated water bath at 4 and 10 mg/L for 2 to 5d respectively. NFLX concentration increased in both the parent and their eggs with the increase of time and concentration of drug exposure and the highest level of NFLX residues were detected in the ovary of parent shrimp. Then the drug residues in the larvae at different developmental stages were further examined. The elimination half-lives of NFLX in Nauplius exposed to NFLX at 4 and 10 mg/L for 24 hours were 45.36 and 49.85 hours respectively and 31.68 and 33.13 hours in zoea, 42.24 and 47.28 hours in Mysis larvae and 24.48 and 30.96 hour in post larvae. Finally, NFLX concentration in shrimp, water and sediment were also examined after drug administration with 2 different ways, medicated bath and feed. NFLX residues were mostly found in sediments and the elimination half-lives of NFLX in the muscle of shrimp exposed to drug by medicated bath and feed were 40.19 and 31.01 hours respectively.