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Study of bio-distribution of encapsulated ytterbium nanoparticles for solid tumors treatment in mice
5th International Conference on Nanotek & Expo
November 16-18, 2015 San Antonio, USA

Navideh Aghaei Amirkhizi1, Fariba Johari Daha2, Leila Moghaddam Banaem2, Mitra Athari Allaf1 and Sodeh Sadjadi2

1Islamic Azad University, Iran 2Nuclear Science and Technology Research Institute, Iran

Scientific Tracks Abstracts: J Nanomed Nanotechnol

Abstract:

We have studied synthesis and characterization of poly (amidoamine) PAMAM G5 encapsulated ytterbium nanoparticles. We have developed a method for the synthesis of dendrimer encapsulated 175Yb nanoparticles in order to produce nanoradiopharmaceutical with irradiation in research reactor. The results of UV-Vis absorption spectra, High Resolution Transmission Electron Microscopy (HRTEM), Dynamic Light Scattering (DLS) and quality control tests of irradiation showed the formation of nano-radiopharmaceutical. The bio distribution of ytterbium nanoparticles in mice that had solid tumors have been studied. The results demonstrate the treatment of solid tumors by ytterbium nanoparticles.

Biography :

Navideh Aghaei Amirkhizi completed her PhD from Science and Research Branch, Islamic Azad University of Tehran, Iran. She is a Researcher in Nuclear Science and Technology Research Institute, and researches about radiopharmaceutical. Her PhD thesis was about production of two nano-radiopharmaceuticals for solid tumors. She has published more than 25 papers.

Email: aghaeinavi@yahoo.com

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