Journal of Stem Cell Research & Therapy

Stem cell therapy for myocardial infarction: Challenges and prospects

4^th International Conference and Exhibition on Cell & Gene Therapy

August 10-12, 2015 London, UK

Gizaw Dabessa

Posters-Accepted Abstracts: J Stem Cell Res Ther

Abstract:

Myocardial infarction causes death worldwide with the greatest incidence being in the United States. Although there have
been many advances in myocardial re-perfusion strategies and novel pharmacological approaches, therapies for treating
acute and chronic myocardial ischemic damage remain limited. This means that no currently available heart failure treatment
has demonstrated an ability to generate new muscle tissue within the scared regions of the heart. Stem cell, however, offers new
hope to patients who have otherwise limited choices. Therefore, this review aims at exploring the use and peculiarities of stem
cell therapy for myocardial infarction. But the success of stem cell therapy for clinical use needs the validation of several issues
ranging from selection of appropriate stem cells, routes of transfer, establishment of conducive trans- differentiation milieu
with associated cytokines, means to evaluate/track response to cell therapy to compliance with regulatory and ethical issues
besides addressing biological and technical issues surrounding stem cell therapy.