Oral Health and Dental Management

Spectrum of salivary glands lesions in pakistan: six years data from the largest government based reference laboratory of sindh, pakistan

6^th Indian Dental Congress

November 23-25, 2015 Bengaluru, India

Syed Muhammad Ali Naqvi1,Talat Mirza2, Anwar Ali3, TazeenMustansar4 and Muhammad Asif Qureshi5

Dow University of Health Sciences, Pakistan

Posters-Accepted Abstracts: Oral Health Dent Manag

Abstract:

Background: The spectrum of salivary gland lesions is wide and the relative prevalence of neoplastic versus non-neoplastic lesions is variable in different studies. The diagnosis of salivary glands lesions, usually presenting as a facial or neck lump, is a clinical dilemma for surgeons and histopathologists due to their unique anatomical location. Data regarding spectrum of salivary gland lesions is scanty in Pakistan. This study will therefore pool data into national and international statistics for salivary gland disorders. Objectives: To describe Pathology based spectrum of salivary gland-lesions in Pakistani population. Settting: A six years observational study conducted at the Department of Histopathology, Dow diagnostic, reference and research laboratory (DDRRL), Karachi. All salivary gland lesions received at the laboratory during 2009-2014 were included in the study. Results: A total of 370 samples were investigated.Of these, a total of 104(28%) were non-neoplastic and 266(72%) were neoplastic lesions. Out of 104 non-neoplastic lesions, 61 cases (58.6%) were of inflammatory origin and 43 (41.3%) were mucoceles. Out of 61 inflammatory lesions, chronic sialadenitis 48 cases (78.6 %) were the most common lesions. Submandibular gland was the most common effected site. For mucoceles, lower lip was the most common site. Of the 266 neoplastic lesions, a total of 209 (78.5%) were benign while 57 cases (21.4%) were malignant. Pleomorphic adenoma was the commonest salivary glands benign neoplastic lesions, 188 (89.9%) followed by benign epidermal inclusion cysts as 6 cases (2.8%) and warthin�??stumour as 4 cases (1.9%). Parotid glands were involved in majority of pleomorphic adenoma cases, 132 (70.2) out of 188 cases.In malignant tumours, 21 cases (36.8%) of Adenoid cystic carcinoma were the most common salivary gland malignant neoplastic lesion, 18 cases (31.5%) were mucoepidermoid Conclusion: Chronic sialadenitis was the most common non-neoplastic lesion, pleomorphic adenoma was the most common benign lesion and adenoid cystic carcinoma (followed by mucoepidermoid carcinoma) was the most common malignant lesion. Keywords: Chronic Sialadenitis, Mucoceles, Pleomorphic Adenoma, Adenoid cystic carcinoma, Mucoepidermoid carcinoma Parotid gland, Submandibular gland