Biochemistry & Analytical Biochemistry

Serum albumin levels in acute stroke: Correlation with clinical outcome

Global Congress on Biochemistry, Glycomics & Amino Acids

December 08-09, 2016 San Antonio, USA

Salman Varmaghani, Mohamad khalili and Pouran Karimi

Institute of Rab-Rashid, Iran
Tabriz University of Medical Sciences, Iran

Posters & Accepted Abstracts: Biochem Anal Biochem

Abstract:

Introduction & Aim: Lower levels of albumin are related to worse prognosis of stroke. Also, evidence has shown that albumin therapy reduces mortality after stroke. Since there are so many discrepancies on the association between serum albumin levels and stroke outcomes, this study was carried out to investigate the association of serum albumin levels with clinical outcome in acute stroke. Methods: In current case control study, 300 stroked patients aged (71.2±10.8 years of both sexes entered the study consecutively) are involved. Serum albumin levels were estimated by colorimetric assay within 24h after stroke and follow-up interviews were conducted at 2 months post-event to determine stroke outcome. The association between serum albumin levels and stroke outcome was evaluated by Chi-square test (SPSS software 22). Results: Low levels of albumin were significantly associated with poor outcome (score of > 3 on the modified Rankin Scale). The adjusted odds ratio was 0.522 (95% confidence interval, 0.204-1.336; P<0.05). The recurrence of stroke and death rate also was high in patients with low levels of albumin compared with patients with elevated levels of albumin. The reduced levels of serum albumin were significantly associated with poor outcome in the stroke. Conclusions: Low levels of albumin in our study were found to be significantly associated with a negative outcome in acute stroke. So, it seems that the levels of serum albumin can be predicted of stroke outcome.

Biography :

Email: s.varmaghani70@yahoo.com