PMC/PubMed Indexed Articles
Indexed In
- Academic Journals Database
- Genamics JournalSeek
- Academic Keys
- JournalTOCs
- China National Knowledge Infrastructure (CNKI)
- Scimago
- Access to Global Online Research in Agriculture (AGORA)
- Electronic Journals Library
- RefSeek
- Directory of Research Journal Indexing (DRJI)
- Hamdard University
- EBSCO A-Z
- OCLC- WorldCat
- SWB online catalog
- Virtual Library of Biology (vifabio)
- Publons
- MIAR
- University Grants Commission
- Geneva Foundation for Medical Education and Research
- Euro Pub
- Google Scholar
Useful Links
Share This Page
Journal Flyer
Open Access Journals
- Agri and Aquaculture
- Biochemistry
- Bioinformatics & Systems Biology
- Business & Management
- Chemistry
- Clinical Sciences
- Engineering
- Food & Nutrition
- General Science
- Genetics & Molecular Biology
- Immunology & Microbiology
- Medical Sciences
- Neuroscience & Psychology
- Nursing & Health Care
- Pharmaceutical Sciences
Screening of indigenous environmental bacteria for production of bioactive compounds (BaCs) and their genes
World Congress and Expo on Applied Microbiology
August 18-20, 2015 Frankfurt, Germany
Nadia Jamil1,3, Nuzhat Ahmed2 and Hartmut Laatsch3
1University of Karachi, Pakistan 2National Institute of Blood Diseases and Bone marrow Transplantation, Pakistan 3Der-George August University, Germany
Posters-Accepted Abstracts: J Microb Biochem Technol
Abstract:
Our environment is a rich source of microorganisms Ñ?ncludÑ?ng bacteria and fungi that can produce sÑ?gnÑ?ficant bioactive compounds (BaCs). These microbes have been shaping their environment and thus the earthâ??s bÑ?osphere for bÑ?llÑ?ons of years through an enormous range of BaCs. These days, as a result of far-reachÑ?ng research, the study of mÑ?crobÑ?al BaCs Ñ?s recognÑ?zed as an essentÑ?al component of natural products chemÑ?stry and as well as consÑ?derable envÑ?ronment frÑ?endly compounds, whÑ?ch have varÑ?ous Ñ?ndustrÑ?al and agrÑ?cultural applÑ?catÑ?ons. Ð?n PakÑ?stan the knowledge regardÑ?ng the Ñ?ndÑ?genous mÑ?crobes capable of producÑ?ng BaCs is in very early stages. Our purpose of this study was to screen two microbes CMGN122 and CMGN370 isolated from Sindh, Pakistan for production of BaCs and their genes. Biological screening samples from microbial fermentation extracts were obtained after optimizing growth conditions and extraction procedures that capture BaCs produced. Column chromatography (CC) and TLC were used for isolation and compound identification and, structure elucidation was done by different techniques of NMR and Mass Spectrometry. CMGN122 identified as Pseudomonas aeruginosa (GenBank Accession No. JN969597) was found to produce three different Phenazine compounds and pyrroloquinoline quinone (Pqq). CMGN370 identified as Candida sp. (GenBank Accession No. JN969598) showed production of two compounds Daidzein and N-(5-Acetylamino-pentyl)-acetamide. Genes for phenazines and PqqC were isolated and amplified.