Journal of Nanomedicine & Nanotechnology

Recent in situ wet cell TEM study on nanomaterials and nano devices

3^rd International Conference on Nanotek & Expo

December 02-04, 2013 Hampton Inn Tropicana, Las Vegas, NV, USA

Xin Chen

Scientific Tracks Abstracts: J Nanomed Nanotechnol

Abstract:

Biosynthesis of metal nanoparticles is an environmentally-friendly method (green chemistry) without use of harsh, toxic and expensive chemicals. After a comprehensive literature review, which was published in a review article and 2 book chapters, we focused our attention to the most promising organisms. Silver nanoparticles were produced at room temperature using biotransformations by 3 novel bacteria, a filamentous fungus, 2 yeasts (1 novel), and 5 novel plants. In case of the bacteria, Lactobacillus casei, L. paracasei, L. rhamnosus , the biosynthesized silver nanoparticles were spherical, single (25-50 nm) or in aggregates (100 nm) attached to the surface of biomass or were inside and outside of the cells. In case of the fungus, Fusarium oxysporum , although this synthesis was not novel, the reaction mixture was successfully optimized to increase the yield of the enzymaticaly produced nanoparticles. The shape and size of the nanoparticles were similar to the case of bacteria. The yeasts, Saccharomyces cerevisiae and S. boulardii (novel) produced mono-dispersed spherical to oval, single (9-26 nm) or aggregated (130 nm) nanoparticles. In case of plants, ethanolic extract of Punica granatum (pomegranate) fruit peel generated single, poly-dispersed, spherical nanoparticles (20-50 nm). Separate ethanolic extracts of Rhus coriaria (Sumac) fruit, Datura metel leaf, and Elaeagnus angustifolia fruit produced aggregated poly-disperse silver nanoparticles with spherical and triangular shapes (20-50 nm). Interestingly, ethanolic extract of Juglans regia ( walnut ) leaf produced single, mono-dispersed, spherical nanoparticles (1-5 nm)

Biography :

Hassan Korbekandi, biotechnologist, graduated from faculty of pharmacy of Isfahan University of Medical Sciences (IUMS), in 1993, and obtained his Ph.D. from chemical engineering department, UMIST University (Manchester) in 2003. He was a member of pharmaceutical biotechnology department since 1993, and now he is working for genetics & molecular biology department of IUMS University. His research interests are bionanotechnology, pharmaceutical biotransformations, protein engineering, bioinformatics and probiotics. He has published 19 papers and 3 book chapters