Journal of Food Processing & Technology

Recent developments in edible vaccines

4^th International Conference and Exhibition on Food Processing & Technology

August 10-12, 2015 London, UK

Renata Slaveska Raichki*, Maja Simonovska Crcarevska and Maja Glavash

Posters-Accepted Abstracts: J Food Process Technol

Abstract:

In the filed of novel strategies for vaccines development with a promising route for noninvasive administration, the concept of
using plants for vaccine expression and delivery has been receiving considerable scientific attention. Over the past years, this
unique challenge has almost created the impressive list of different antigens expressed in transgenic plants and plant cell culture
systems. Thus, for example, transgenic plantderived vaccinogens includes hepatitis antigen in potatoes and a lettuce, a rabies
antigen in tomato and E. coli heat–labile enterotoxin in corn. Moreover, carrots, maize, banana and other food plant-based
production systems have been involved in the development of edible vaccines. As acknowledge, the first human clinical trials
for a transgenic, plant-derived antigen were approved (Food and Drug A) and performed in 1997. It is reported that delivery
of a plant-derived vaccine to a mucosal tissue induces both a mucosal and a systemic immune response. The recent advances
achieved in this field with long-term potential addressing dosage, best delivery method, strength as well as advantages and
current limitations are demonstrated and evaluated.
Key words: edible vaccines, advantages and limitations

Biography :

Renata Slaveska Raichki is a pharmacist and full Professor in Pharmaceutical Technology and Biotechnology at the Faculty of Pharmacy, Ss. Cyril and Methodius
University in Skopje, Macedonia. She completed MSc degree at the University of Zagreb in 1990, health specialization in 1995 and PhD degree at the Ss. Cyril and
Methodius Universityin 2001. Her research interests focus on themass transfer, method development and experimental design. She published more than fifty papers in
domestic and foreign scientific journals; participated at more than thirty scientific and professional meetings in the country and abroad. She was involved of many domestic
and international scientific projects in the field of natural product and drug science.