Journal of Vaccines & Vaccination

Prevalence of ESBL Escherichia coli in urinary tract infections

International Conference & Exhibition on Vaccines & Vaccination

22-24 Nov 2011 Philadelphia Airport Marriott, USA

Wanda C. Reygaert

Scientific Tracks Abstracts: J Vaccines Vaccin

Abstract:

Th e most common cause of urinary tract infections (UTIs) is Escherichia coli. Antimicrobial resistance rates among these isolates is highly varied and rapidly increasing, and it is vital to characterize these isolates as to the frequency of serious antimicrobial resistance patterns, and in particular, extended spectrum beta-lactamase (ESBL) producers. ESBL strains are oft en commonly resistant to other drug classes as well, and for that reason, treatment options may be very limited. Because of this, UTIs caused by ESBL strains can result in increased healthcare costs. Antimicrobial resistance data has been collected from nearly 1500 UTI E. coli isolates in the Detroit, Michigan metropolitan area. Th is data has been analyzed to determine the frequency of resistance to the various drugs, the frequency of resistance to the diff erent drug classes, and the frequency of resistance based on the antimicrobial eff ects of the various drugs. Th e characterization of this type of data can lead to a better understanding of treatment options for UTIs, and hopefully lead researchers in the right direction for new antimicrobial and/or vaccine development.

Biography :

Wanda Reygaert has a Ph.D. in Molecular Biology from the University of Illinois at Chicago, has taught at Oakland University since 2004 where she has conducted research on urinary tract infection isolates. She is currently the Discipline Director for Microbiology and Immunology at the OUWB School of Medicine. She also has a degree in Medical Technology and was employed in clinical laboratories for over 12 years, 5 of those years as a clinical microbiologist