Journal of Vaccines & Vaccination

Pork industry intensifi cation and the changing ecology and epidemiology of swineorigin infl uenza

International Conference & Exhibition on Vaccines & Vaccination

22-24 Nov 2011 Philadelphia Airport Marriott, USA

Michael Greger

Scientific Tracks Abstracts: J Vaccines Vaccin

Abstract:

Th e 2009 swine-origin infl uenza virus A subtype H1N1 (S-OIV) pandemic resulted in an alarming increase in pediatric infl uenza mortality. According to phylogenetic analyses, each segment of the S-OIV genome derives from swine infl uenza lineages circulating primarily in pigs for at least a decade before the pandemic emerged. Considerable genetic and antigenic stability had characterized most swine infl uenza virus isolates in North American for 80 years before the emergence of the primary progenitor of S-OIV, the triple re assortments wine fl u virus fi rst identifi ed in U.S. pig herds in 1998, which became established throughout North America and generated further re assortment viruses and sporadic human infection. Changes in industry structure and husbandry practices that may have played a role in this shift ing dynamic are explored. Identifying and resolving confl icting priorities between veterinary and public health professions can bolster the One Health vision and may help prevent the emergence and spread of pathogens with pandemic potential