Journal of Nanomedicine & Nanotechnology

PLGA-based nanostructures at biological interfaces: current status and prospects

26^th International Conference on NANOMATERIALS

December 05-06, 2022 | Dubai, UAE

Juhi Saxena

Chandigarh University, India

Keynote: J Nanomed Nanotechnol

Abstract:

The development of PLGA-based polymeric nanoparticulate structures as smart drug delivery systems (SMART-DDS) is revolutionary. These structures at their nanoscale size exhibit excellent properties for biological interfaces involving biocompatibility, bioavailability, controllable targeting, penetration, and tunable release of drugs. PLGA can be copolymerized with other polymers to attain stable complexes. Many PLGA-based nanomaterials have received FDA approval due to inimitable features which enable the encapsulation of hydrophobic and hydrophilic drugs for biomedical applications. Nano-PLGA structures have reduced toxicity and better colloidal stability at subcellular levels. They are best suited as scaffolds and drug carriers however process optimization through various synthesis routes can potentiate their properties to be exploited as multifunctional DDS in Theranostics areas.
Recent publications :
1. Kumar, S., Saxena, J., Srivastava, V. K., Kaushik, S., Singh, H., Abo- EL-Sooud, (2022). The Interplay of Oxidative Stress and ROS Scavenging: Antioxidants as a Therapeutic Potential in Sepsis. Vaccines, 10(10), 1575.
2. Saxena, J., Bisen, M., Misra, A., Srivastava, V. K., Kaushik, S., Siddiqui, A. J, and Jyoti, A. (2022). Targeting COPD with PLGA-Based Nanoparticles: Current Status and Prospects. Biomed Research International, 5058121-5058121.
3. Raghav, D., Jyoti, A., Siddiqui, A. J., & Saxena, J. (2022). Plant associated endophytic fungi as potential bio-factories for extracellular enzymes: Progress, Challenges and Strain improvement with precision approaches. Journal of Applied Microbiology.

Biography :

Saxena J has completed her Ph.D. at the age of 34 years in 2018 from Manipal University, Jaipur campus, India. She is the assistant professor, Department of Biotechnology, UIBT of Chandigarh University, India. She has over 20 publications with H-index- 8 and has served as reviewer of reputed journals.