Cardiovascular Pharmacology: Open Access

Physical capacity in children with congenital heart disease: Experience of a Chilean pediatric cardiovascular center

15^th International Conference on Pediatrics and Pediatric Cardiology

February 19-20, 2018 | Paris, France

Bernardita Lopetegui, Mercedes Guevara, Roberto Acosta Dighero and Rodrigo Torres-Castro

Dr. Luis Calvo Mackennaâ??s Children Hospital-University of Chile, Chile
San Sebastian University, Chile
University of Chile, Chile

Posters & Accepted Abstracts: Cardiovasc Pharm Open Access

Abstract:

Introduction & Aim: Physical capacity assessment is an essential tool for the characterization, prognosis, and response to treatment in children with congenital heart disease (CHD). The diminished physical capacity increases the risk of cardiovascular disease and the acquisition of other comorbidities associated to inactivity. This research aimed to describe the physical capacity in children with CHD in a specialized pediatric cardiovascular center in Chile. Methods: We review the clinical records, and cardiopulmonary exercise test (CPET) of patients admitted between 2015 and 2017 in Cardiovascular Center of Dr. Luis Calvo Mackenna Childrenâ??s Hospital in Santiago of Chile. We describe the anthropometric measures and the following physical capacity outcomes: Peak oxygen uptake (VO2 peak), work rate peak (WRpeak) and heart rate peak (HRpeak). We used the SPSS v23.0 software for the statistical analysis. Results: We analyzed the CPET of 166 children: 137 with CHD and 29 without CHD, in which 107 were boys. Mean age was 13.1±2.4 years; mean height was 155 cm (144-164), mean weight was 48 Kg (40-58). Mean Body Mass Index was 20.7±3.9 (Z-Score +0.5±1.4). VO2 peak was 28.0 (24.0-32.0) ml/Kg/min for CHD-group and 34.0 (27.0-41.0) ml/Kg/min in nonCHDgroup (p=0.001). This difference also exists between each CHD-subgroup and nonCHD-group. The WRpeak was 144.7±52.4 watts for CHD-group and 180.3±47.3 watts for the nonCHD-group (p=0.001), and HRpeak was 164 bpm (142-177) for CHDgroup and 174 bpm (147-190) for the nonCHD-group (p=0.06). Conclusion: VO2 peak and WRpeak were lower in children with CHD respect the nonCHD.

Biography :

Bernardita Lopetegui has completed her Pediatric Cardiology Fellowship from University of Chile and had Electrophysiology training. She is the Head of Arrhythmia’s section of Dr. Luis Calvo Mackenna’ Children Hospital. She is the Assistant Professor and Deputy Head of Pediatric Cardiology Fellowship from University of Chile School of Medicine.