Journal of Bacteriology & Parasitology

Outbreak of hepatitis E in Sambalpur, Odisha in 2014

4^th International Congress on Bacteriology and Infectious Diseases

May 16-18, 2016 San Antonio, USA

Amol A Patil, V Katoch, A Shrivastava and S Venkatesh

National Center for Disease Control, India

Posters & Accepted Abstracts: J Bacteriol Parasitol

Abstract:

Hepatitis E virus (HEV) is the leading cause of acute viral hepatitis in developing countries where fecal contamination of drinking water is common. In November 2014, Sambalpur district reported an outbreak of hepatitis E. We defined a case of a person with acute onset of jaundice and at least one of six symptoms (fever, dark urine, anorexia, malaise, extreme fatigue or right upper quadrant tenderness) from 1st May 2014-30th December 2014 residing in Sambalpur municipality. We conducted a house to house survey to find cases and did an unmatched case control study. Controls were selected from neighborhood. We collected blood and water samples. Among 365 patients, including 7 deaths, 244 (67%) were in the 15-44 year age group and 239 (66%) were male. Illness onset dates ranged from 17 May 2014 to date of investigation. Among 19 blood samples, 12 tested positive for IgM anti-HEV; all were negative for IgM anti-hepatitis A virus. Among 113 cases and 113 controls, consuming non-purified water (odds Ratio (OR) 1.9, 95% Confidence Interval (CI) 1.1-3.2), drawing water with mug/ladle from storage container (OR 2.6, 95% CI 1.2-6.1) and eating from street side vendor OR 2.0, 95% CI 1.2-3.5) were significantly associated with illness. Among 24 water samples around the municipality, 12 were positive for fecal coliforms. In outbreak, hepatitis E was associated with common practices and personal habits. We recommend purifying water such as through boiling, using containers with taps for storing drinking water and avoiding food from street vendors.

Biography :

Email: amol.patil0377@yahoo.co.in