Journal of Food Processing & Technology

Onosma aucheriana dc. As a novel sources of biologically important molecules

4^th International Conference and Exhibition on Food Processing & Technology

August 10-12, 2015 London, UK

Pavle Maskovic*1, Mirjana Menkovska2, Desimir Knezevic 3 and Lazari Diamanto 4

Posters-Accepted Abstracts: J Food Process Technol

Abstract:

The objectives of this study were to define the phenolic profile, antioxidant, antimicrobial and cytotoxic properties of O.
aucheriana extracts, which has never been comprehensively examined before. HPLC-DAD assay system was used in order
to define the polyphenolic profiles of obtained extracts. Among all other identified compounds, the most dominant were
rosmarinic acid, galic acid and p-hydroxybenzoic acid. Antioxidant activity was determined by five different assays. All results
were comparable to well-known synthetic antioxidants. Antimicrobial properties of extracts were examined using 23 selected
indicator strains and for all extracts minimum inhibitory concentration were in the range between 7.81 and 62.50 μg/ml. Using
three different cells: human rhabdomyosarcoma cells (RD), cell line derived from human cervix carcinoma Hep2c (HeLa) and
cell line derived from murine fibroblast (L2OB), cytotoxic activity of examined extracts was determined. The IC50 values for
observed extracts ranged from 25.54 to 40.34 μg/ml. Soil and extracts of O.aucheriana were analyzed for the content of micro,
macro and toxic elements by inductively coupled plasma mass spectrometry (ICP-MS). Obtained results showed the presence
of heavy metals within permissible limits. Furthermore, the presence of any pesticides in the soil or in plant extracts was not
identified.

Biography :

Pavle Maskovic is Associate Professor in Chemistry from 2012. On the Faculty of Argonomy, �?ačak, University of Kragujevac. At 2015 he finished post doctorial studies
at Aristotle University of Thessaloniki, Faculty of Pharmacy, Department of Pharmacognosy, Thessaloniki, Greece. He finished Ph.D. studies in Chemical Sciences, Major
in Biochemistry, Faculty of Natural Sciences and Mathematics, University of Kragujevac. RESEARCH AREAS OF INTEREST: Microbiological Chemistry, Chemistry of
Natural Products, Plant Biochemistry, Biochemistry of Primary and Secondary Metabolites.