Journal of Nanomedicine & Nanotechnology

Novel sol-gel preparation of binary (TiO2)(x)-(P2O5)(100-X) nanospheres via electrospraying for biomedical application (x=40, 45, 50)

4^th International Conference on Nanotek & Expo

December 01-03, 2014 DoubleTree by Hilton Hotel San Francisco Airport, USA

Farzad Foroutan, Nora de Leeuw and Jonathan C Knowles

Accepted Abstracts: J Nanomed Nanotechnol

Abstract:

A new sol-gel preparation method has been followed for making binary titanophosphate nanosphere glasses (NSGs) at low temperature. Binary glasses were prepared using triethyl or n-butyl phosphate and spayed via a high electric field to obtain NSGs. The structure of the NSGs was probed using X-Ray diffraction (XRD), 31P nuclear magnetic resonance (31P-NMR), Fourier transform infrared spectroscopy (FTIR). The elemental proportion has been characterized using energy dispersive x-ray spectroscopy (EDX) and the particle size of the spheres were measured via scanning electron microscopy (SEM). The XRD results confirmed the amorphous nature of the NSGs. The 31P-NMR and FTIR spectra demonstrated that the glass structure consists of mainly Q1 and Q2 species. The EDX results showed higher loss of phosphorus for the samples madewith triethyl phosphate compare to n-butyl phosphate as a phosphorous precursor and SEM images confirmed the submicron particle size range of 100-200 nm. These results provide several interesting insight indicates the suitability of these sol-gel glasses for biomedical application, specifically to incorporate proactive molecules into these glasses for drug delivery application, since these glasses can be synthesised at low temperature. And also they can be considered as an antimicrobial and coating for biomedical devices whenever a medical device comes into direct contact with living tissue or body fluid.