Pharmaceutica Analytica Acta

Novel high performance polymer-based anion exchangers for ion chromatography

International Conference and Exhibition on Advances in HPLC & Chromatography Techniques

March 14-15, 2016 London, UK

Aleksandra Zatirakha

Lomonosov Moscow State University, Russia

Scientific Tracks Abstracts: Pharm Anal Acta

Abstract:

Since the introduction of ion chromatography (IC), this method has developed into the most powerful tool for the determination of inorganic and organic anions of low and high molecular weight. In the last decade the developments in the field of IC were aimed at increasing efficiency, sensitivity and rapidity of analysis, as well as at improving separation selectivity. Since selectivity and efficiency to the large extent depend on the surface chemistry of the stationary phase, the development of novel anion exchangers remains one of the priority tasks in modern IC. Anion exchangers for suppressed IC should be mechanically stable and withstand high pH values, which makes aromatic copolymers such as polystyrene-divinylbenzene (PS-DVB) or ethylvinylbenzene-divinylbenzene (EVB-DVB) the most suitable supports for obtaining such stationary phases. Chemical derivatization of polymer surface is considered to have certain restrictions in terms of providing high efficiency; however, some modern IC columns show that such technique can certainly be used for obtaining high performance anion exchangers. Novel chemically derivatized polymeric anion exchangers developed at Chemistry Department of Lomonosov Moscow State University are compatible with hydroxide eluents and enable efficient and selective separation of 15 anions in 30 minutes, including oxyhalides (chlorite, chlorate, bromate), weakly retained organic acids (glycolate, acetate, formate, propionate), so-called standard inorganic anions (fluoride, chloride, nitrite, bromide, nitrate, phosphate and sulphate), and carbonate. The variation of the functional ion-exchange layerâ??s structure provides the possibility to easily govern selectivity and efficiency of the obtained anion exchangers.

Biography :

Aleksandra Zatirakha graduated from Chemistry Department of Lomonosov Moscow State University, Moscow, Russia, in 2008 and received her PhD in 2011. She currently holds the position of researcher at Chemistry Department, where she works in the group of design and application of new materials for HPLC separations, and also teaches Analytical Chemistry for the students. Her main interests are stationary phase design and ion chromatography, and her research is focused on the development of anion exchangers for ion chromatography and stationary phases for HILIC.

Email: zatirakha@analyt.chem.msu.ru