Journal of Nanomedicine & Nanotechnology

Magnetic and optical properties of PEG and dextran coated magnetic nanoparticles

11^th International Conference and Expo on Nanoscience and Molecular Nanotechnology

October 20-22, 2016 Rome, Italy

V Mikelashvili, Sh Kekutia, J Markhulia, L Saneblidze, Z Jabua, D Daraselia and D Jafaridze

Vladimir Chavchanidze Institute of Cybernetics of the Georgian Technical University, Georgia
Georgian Technical University, Georgia
Tbilisi state university, Georgia

Posters & Accepted Abstracts: J Nanomed Nanotechnol

Abstract:

The development of the synthesis of stable aqueous suspensions of superparamagnetic iron oxide nanoparticles stabilized with unmodified polyethylene glycol (PEG) at two molecular weights (4000 and 6000 Da) and dextran-40 has been reported. The obtained biocompatible polymer (PEG)m and dextran coated nanoparticle dispersive solution with pH â?? 6.5 and solid phase content ranging from 0.02-0.75 % w/v has been investigated for optical and magnetic properties. Biomedical application requires the biocompatible superparamagnetic iron oxide nanoparticles (SPION), which are stable and well dispersed in water at physiological pH or in physiological salinity. Biocompatible 10-20 nm sized SPIONs have been synthesized via co-precipitation method in the vacuum environment. These SPIONs have been modified with PEG and dextran in one-pot synthesis. Vibrating Sample Magnetometer (VSM) studies show the effect of phase transformations on the magnetic properties of the nanoparticles and surfactant influence on the characteristic of the magnetization at room temperatures into high and low magnetic fields.

Biography :

Email: vmikelashvili@gtu.ge