Journal of Stem Cell Research & Therapy

Knee Ortho Biologics: New developments which may delay or avoid more invasive surgical treatments? The future of orthopaedics? Basically, less carpentry, more biology?

17^th World Congress on Tissue Engineering, Regenerative Medicine and Stem Cell Research & 10^th Global Conference on Physiotherapy, Physical Rehabilitation and Sports Medicine

October 28, 2022 | Webinar

Prithiv K R Kumar

Hiorca Stem Cell Research Centre, USA

Posters & Accepted Abstracts: J Stem Cell Res Ther

Abstract:

Trisomy silencing is an important factor in curing Down syndrome. As per study in various experiments XIST transgene transforms chromosome 21 in stem cells. This transgene normalises cell function and development upon transformation and its induction in transgene clones corrects the over production of meakayocytes, stem cells, iPS cells and erythrocytes keeping balance of haemopoietic developments. Given all these to added knowledge, our study further advanced to CD4/CD43 progenitors cells demonstrating principle proof for epigenetic based investigative strategy in pathology. Chapter basic focus on drug discovery, delivery of drugs, administration path, dosage and frequency of transplantation. Monitor tools of MRI, MSK and PET-CT scanners. Also cultivation of chromosome 21 cells trisomy to disomy is relevant without genetic manipulation, chemical treatment and exposure to irradiation. Disomy or diploid cells serve to the purpose of drug screening and raw material of regenerative medicine and cell based therapy.