Cardiovascular Pharmacology: Open Access

Investigation of congenital heart disease in children with cleft palate: A cross-sectional study

Joint Event on Heart Failure, Pediatric Cardiology & Nursing Education

February 18-19, 2019 | Amsterdam, Netherlands

Amirreza Dehghan

Mashhad University of Medical Sciences, Iran

Posters & Accepted Abstracts: Cardiovasc Pharm Open Access

Abstract:

Objective: Oral clefts is one of the most common congenital craniofacial deformities seen in children (1 per 700 live births). Lots of congenital anomalies are associated with this condition and some literatures reported congenital heart diseases to be the most commonly associated congenital deformity with oral clefts. The importance of cardiac sufficiency in oral cleft plastic surgeries led us to study the prevalence of different types of congenital cardiac anomalies/defects in cleft lip and palate patients.

Methods & Materials: A cross-sectional survey was conducted among 122 oral cleft patients who were referred to Mashhad University of Medical Sciences for surgical treatment. The study took place between 2014 to 2015. Data acquired from medical history, examination and echocardiography reports were collected and analyzed by SPSS software version 20.

Results: Out of 122 patients of cleft lip and palate, 70 patients (57.4%) were associated with congenital cardiac anomalies with male to female ratio of 1:1. The most common type of cardiac anomaly was VSD (20.5%) and the most common type of coronary anomalies was PFO (33.6%). Associated congenital cardiac anomalies were most frequently seen in children from consanguineous marriages.