Gerontology & Geriatric Research

Investigation into age-related formulations-focus on geriatric patient populations

2^nd International Conference on Geriatrics & Gerontology

August 24-26, 2015 Toronto, Canada

Luigi Martini F R

King�??s College London, UK

Posters-Accepted Abstracts: J Gerontol Geriat Res

Abstract:

Increasing life expectancy and the aging �??baby-boomer�?� generation are leading to a challenging demographic shift in our society over the next decades. Overall the increasing life expectancy and higher age are correlated with a higher probability of functional declines and potential disabilities that have consequences across the various domains of independent life and care giving. There is no doubt that the oral route is the most preferred route in the administration of medicinal products and drug therapy. The active moieties are formulated and processed into solid oral dosage forms (SODF) like tablets and capsules that are swallowed as such to release its content by disintegration and dissolution of the drug in gastrointestinal fluids for absorption. There are several advantages related to SODF like dose accuracy, various opportunities to provide different release profiles, facilitated drug distribution, non-invasiveness and ease of use by the patients. It is evident therefore that enormous scope still exists to design by first intent an oral delivery system designed for geriatric populations and which can accommodate a wide range of drug properties (dose, aqueous/lipid solubility and taste) and circumvent a number of geriatric diseases such as dry mouth, dysphagia. In the first instance, the candidate will investigate a number of colloidal/micro emulsions based delivery systems and apply a number of physico-chemical characterization techniques.

Biography :

Email: luigi.martini@kcl.ac.uk