Christian Enzensberger
Justus-Liebig University of Giessen, Germany
Posters & Accepted Abstracts: Cardiovasc Pharm
Introduction & Purpose: Frame rates (FR) used for strain analysis assessed by speckle tracking in fetal echocardiography show a huge variation. Due to higher heart rates compared to adults, much higher FR is requested in fetuses. The aim of this study was to investigate the influence of the FR on strain analysis in two-dimensional (2D) speckle tracking. Material & Methods: A prospective cross-sectional study was performed. Based on an apical or basal four-chamber view of the fetal heart, cine loops were acquired on a Toshiba Aplio 500 system. Each loop was digitally stored twice: firstly as a DICOM (digital imaging and communications in medicine) file with a FR of 30 frames per second (fps), secondly with the original FR (acoustic FR=AFR). For each loop, fetal global longitudinal peak strain values of both, left (LV) and right ventricle (RV), were assessed by 2D wall motion tracking. Strain analysis was performed offline by two investigators. Interobserver variability was analyzed. Results: A total of n=11 healthy fetuses with an echocardiogram performed between 19 and 34 weeks of gestation were included. The AFR was 126±16 fps. Relating to global longitudinal peak strain values of both ventricles, there was no significant difference between DICOM FR and AFR (LV: -18.22% (DICOM FR) vs. -17.77% (AFR), RV: -16.30% (DICOM FR) vs. -15.28% (AFR); p>0.05). The interobserver variability showed a strong agreement with an intraclass correlation coefficient (ICC) of >0.8. Conclusions: The influence of the FR on global longitudinal peak strain values in 2D speckle tracking seems to be less important than expected. For strain analysis in fetal echocardiography FR of >100 fps seem to be non-essential.
Email: cenzensberger@googlemail.com