Indexed In
- Open J Gate
- Genamics JournalSeek
- Academic Keys
- JournalTOCs
- ResearchBible
- Electronic Journals Library
- RefSeek
- Hamdard University
- EBSCO A-Z
- OCLC- WorldCat
- Proquest Summons
- SWB online catalog
- Virtual Library of Biology (vifabio)
- Publons
- MIAR
- Euro Pub
- Google Scholar
Useful Links
Share This Page
Journal Flyer
Open Access Journals
- Agri and Aquaculture
- Biochemistry
- Bioinformatics & Systems Biology
- Business & Management
- Chemistry
- Clinical Sciences
- Engineering
- Food & Nutrition
- General Science
- Genetics & Molecular Biology
- Immunology & Microbiology
- Medical Sciences
- Neuroscience & Psychology
- Nursing & Health Care
- Pharmaceutical Sciences
Impacts of previously established loci associated with obesity-related traits on type 2 diabetes
2nd International Conference on Predictive, Preventive and Personalized Medicine & Molecular Diagnostics
November 03-05, 2014 Embassy Suites Las Vegas, USA
Joo-Yeon Hwang, Juyoung Lee and Bong-Jo Kim
Posters: J Pharmacogenomics Pharmacoproteomics
Abstract:
To date, genetic predispositions to type 2 diabetes (T2D) underlying obesogenic environments have demonstrated genetic heterogeneity across global populations. To extend understanding of the overall genetic architecture, we recapitulated previous obesity-related susceptibility loci on T2D risk in two ethnic-different consortiums (the DIAGRAM and the AGENT2D). A total of 64 SNPs in or near 41 genes were observed with pleiotropic associations on T2D (9 trans-ethnic, 22 Europeanspecific and 10 Asian-specific). In a conditional analysis, 14 genes were found to be associated with T2D risk in obesityindependent manner. In conclusion, our findings might expand understanding of multiple genetic effects in metabolic and endocrine regulation.