Ashish Ranjan
Accepted Abstracts: J Nanomed Nanotechnol
Cancer chemotherapy usually relies on systemic delivery with limited tumor specificity, and therefore may result in adverse side effects in normal tissues and insufficient drug delivery to the target tumor. Image-guided drug delivery is exciting and emerging fields that can enhance spatial targeting, detect and measure drug release using markers co-loaded with drugs within the nanocarriers, and improve targeting when compared with more traditional drug delivery strategies. Various imaging modalities such as ultrasound and MRI can provide acquisition of anatomic targets structure for treatment planning, accurate thermometry for treatment monitoring and control, and real-time monitoring of intratumoral drug release. Our studies show that combination of MRI and ultrasound technology with thermosensitive nanocarriers results in enhanced tumor drug delivery and distribution. This technology has significant potential for clinical translation.
Ashish Ranjan obtained his Ph.D. from Virginia Polytechnic Institute and State University and postdoctoral studies from National Institutes of Health, MD. He is an Assistant Professor in the Center for Veterinary Health Sciences, Oklahoma State University. He has published/presented more than 50 articles and has been serving as an editorial board member of repute in Journal of Nanomedicine and Biotherapeutic Discovery (JNBD) and Advances in Dairy Research