Journal of Aquaculture Research & Development

Genomic advances and applications in aquaculture

2^nd Global Summit on Aquaculture & Fisheries

July 11-13, 2016 Kuala Lumpur, Malaysia

Zhanjiang John Liu

Auburn University, USA

Posters & Accepted Abstracts: J Aquac Res Development

Abstract:

The channel catfish genome has been completely sequenced. In this presentation, progress related improvements of whole genome sequence assembly, scaffolding, and construction of chromosome-level sequence builds will be presented. With the draft or reference genome sequences, the relationship of whole genome variations and performance or production traits can be dissected using RNA-Seq, bulk segregant RNA-Seq (BSR-Seq), or genome-wide association studies (GWAS). We have devoted much effort towards understanding the catfish disease resistance and low oxygen tolerance using genomic approaches including genome sequencing, assembly and annotation, expression after bacterial infection and low oxygen challenge. Earlier research focused on a large set of known genes using microarrays, whereas our most recent studies have adopted the next generation sequencing approaches such as RNA-Seq, BSR-Seq, and GWAS for the analysis of candidate genes involved in disease resistance and low oxygen tolerance. Harnessing genomic techniques, especially GWAS work using the high density 250K SNP array, and ongoing work for the development of the 690K SNP array, and BSR-Seq promise both a better understanding of teleost disease resistance and low oxygen tolerance, and the potential for practical applications in aquaculture..

Biography :

Email: liuzhan@auburn.edu