Brain Disorders & Therapy

Evaluation of the role of ischemia modified albumin as a new biochemical marker for differentiation between ischemic and hemorrhagic Stroke

Global Summit on Stroke

August 03-05, 2015 Birmingham, UK

Nany Hassan Abu Al Makarim, Mohamed Samy Gad and Nermeen Hosam El-Din Zakaria

Scientific Tracks Abstracts: Brain Disord Ther

Abstract:

Objective: To evaluate the role of the detection of ischemia modified albumin (IMA) level in the differentiation between
ischemic and hemorrhagic cerebrovascular stroke.
Materials & Methods: Sixty elderly persons classified into three groups, 25 patients diagnosed with cerebral infarction, 15
patients diagnosed with cerebral hemorrhage and 20 elderly healthy persons with matched age as control were enrolled in the
study. IMA was measured using the available chemical method and computerized tomography (CT) was done for diagnosis
of brain lesions.
Results: IMA was significantly higher in patient group than control group. There was positive significant correlation between
age, albumin with IMA, (P=0.000 and 0.037 respectively). However there was no statistical significant difference between sex
and diagnosis cross tabulation (0.51). It was found that, IMA was statistically higher in infarction group than hemorrhage group
(P=0.000) and IMD index was statistically higher in infarction group than hemorrhage group (P=0.013). Our investigation in
elderly patients suggests that IMA assay is a sensitive marker for early detection ischemic and hemorrhagic stroke.

Biography :

Nany Hassan Abu Al-Makarim is Lecturer of Internal Medicine, Geriatrics Department at Alexandria University, Egypt. She has done her MS in Rheumatology and
MD in Geriatrics.