Pharmaceutica Analytica Acta

Electrochemical sensing platform toward gaseous hydrogen peroxide and introduction of novel electroanalytical techniques

24^th Global Summit on Analytical and Bioanalytical Techniques

July 19-20, 2023 | Webinar

Nabi Ullah

University of Lodz, Faculty of Chemistry, Department of Inorganic and Analytical Chemistry, Poland

Scientific Tracks Abstracts: Pharm Anal Acta

Abstract:

Hydrogen peroxide is a vital part of many physiological reactions in human body and its concentration can be related to detection of certain diseases such as asthma and lung cancer [1-3]. Among different methods, those based on electrochemistry have gained extensive attention due to, fast response, its sensitivity, and easy handling [4, 5]. In this study, copper mediator (Cu2+ 0.2 mmol/L) is applied in a mixture electrolyte of 0.1 mol/L KNO3, and 1% polyacrylic acid (PAA) for the detection of H2O2 in the concentration range from 0.3 to 10 mmol/L. The optimized reaction conditions show good response for H2O2 detection in reduction mode in cyclic voltammetric studies (CV). The optimized determination condition is applied for square-wave voltammetry (SWV) due to better sensitivity as compared to CV. The SWV for solution H2O2 detection shows LOD and LOQ of 1.17 × 10-4 and 3.89 × 10-4 mol/L, respectively. It is worth noting that new electrochemical techniques for detection have been applied, which are based on SWV. The new techniques electrochemical faradaic spectroscopy (EFS) and differential square-wave voltammetry (DSWV) are more superior to SWV with respect to detection limit and sensitivity factor. EFS shows LOD and LOQ of 1.17 × 10-4 and 3.88 × 10-4 mol/L, while DSWV shows the best response for LOD and LOQ as 9.05 × 10-5 and 3.02 × 10-4 mol/L, respectively. Finally, the optimized conditions of SWV are applied on glassy carbon screen printed electrode (SPE) for the detection of the gaseous sample. The system detects hydrogen peroxide in gaseous phase with LOD and LOQ of 1.50 ×10-5 mol/L and 5.02 × 10-5 mol/L , respectively..

Biography :

Nabi Ullah is currently a postdoctoral fellow at Department of Inorganic and Analytical Chemistry, Faculty of Chemistry, University of Lodz, Lodz Poland. He received his Ph.D. from the School of Chemistry and Chemical Engineering, Jiangsu University, Zhenjiang China, in 2019. His main research area synthesis of 3D grapheme, CNTs, nanomaterials, nanocomposites, and their electrochemical energy conversion and storage applications such as water splitting, super capacitors, and methanol electro-oxidation reaction. Recently, he has been working on electrochemical detection of gas hydrogen peroxide via advanced electrochemical techniques.