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Development of Potent Inhibitory Phage Vaccine against Prostate Cancer
5th Asia Pacific Global Summit and Expo on Vaccines & Vaccination
July 27-29, 2015 Brisbane, Australia
Masoumeh Rajabibbazl
Posters-Accepted Abstracts: J Vaccines Vaccin
Abstract:
In this research we pursue a less studied strategy of using PSMA displaying M13 bacteriophage for vaccination against prostate cancer. Bacteriophage vaccine are able to induce both humoral and cellular immune response, therefore, it is expected that vaccination with these recombinant phage would obliterate the immune tolerance to self-antigens and instigate immune system to attack cancerous cell expressing this antigen. The aim of this study is to investigate the possibility of design and production of phage-based cancer vaccine to induce immune response against prostate cancer.