Development of anti-hyperglycemic poly herbal juice supplement (ADJ6)
7th Indo-Global Summit and Expo on Food & Beverages
October 08-10, 2015 New Delhi, India

Changam Sheela Sasikumar

Frontier Lifeline & Dr. K. M. Cherian Heart Foundation, India

Posters-Accepted Abstracts: J Food Process Technol

Abstract:

Diabetes is a heterogeneous metabolic disorder characterized by altered carbohydrate, lipid and protein metabolism which causes hyperglycemia resulting from insufficient insulin secretion, insulin action or both. Synthetic medicines are available to control and to treat diabetic patients but total recovery from diabetes has not been reported up to this date. Alternative to these synthetic agents many herbal plants with hypoglycemic properties are known from across the world. The World Health Organization (WHO) has listed 21,000 plants which are used for medicinal purposes around the world. Current research around the world is focused on finding an alternative source of treatment from natural resources for diabetic management apart from the available synthetic medicines. Ancient Indian Medicine (AIM), a contribution of our ancestors offers plenty of resources to not only control the diseases but also has the ability to reduce the impact of the chronic ailments with minimal or no side effects. AIM also reminds us to look into our eating processes where it highlights the main aspect â??FOOD as MEDICINE and MEDICINE as FOODâ?. Our aim was to develop an anti-diabetic formulation from edible food materials which can be used as a nutraceutical. Various in vitro assays were carried out including its inhibitory effect against digestive enzymes alpha amylase and glucosidase which are essential for controlling diabetes. Further the formulation was also tested for its anti-hyperglycemic activity against standard animal model which proved that the formulation was very effective in not only controlling the blood glucose levels but also offers protection against diabetes associated damages to various organs such as pancreas, liver, kidney and pancreas. The formulation also renders a significant protection against free radical-induced damage also. The results obtained clearly elucidate that the formulation is effective against hyperglycemia, free radicals and associated pathological damage. Thus the poly herbal formulation can be used as an oral supplement for diabetes in addition to the standard anti-hyperglycemic drugs. Further, we aim to commercialize the product to benefit the people and to add value to the Ancient Indian Medicine since the product is 100% derived naturally.

Biography :

Email: sheelsasic@yahoo.co.in