Journal of Bioequivalence & Bioavailability

Determination of carcinogenic bromate by uplc-ms/ms and its adsorptive removal by using anion exchange resin

4^th World Congress on Bioavailability and Bioequivalence: Pharmaceutical R&D Summit

May 20-22, 2013 DoubleTree by Hilton, Beijing, China

Mu. Naushad

AcceptedAbstracts: J Bioequiv Availab

Abstract:

Contamination of water due to bromate is a severe health hazard. The aim of present study was to remove bromate from water using a crosslinked polystyrene based strongly basic anion exchange resin De-Acidite FF-IP. Batch experiments were performed to study the influence of various experimental parameters such as effect of pH, contact time, temperature and effect of competing anions on bromate removal by De-Acidite FF-IP resin. At optimum parameters the removal rate of bromate was very fast and 90% removal took place in 5 min and equilibrium was established within 10 min. The presence of competitive anions reduced the bromate adsorption in the order of Cl− > F− > CO3 2 − > SO4 2 − > NO3 − > PO4 3 −. The practical utility of this resin has been demonstrated by removing bromate in some of the commercial bottled water from Saudi Arabia. The level of bromate was determined using a very sensitive, precise and rapid method based on ultra-performance liquid chromatography-tandem mass spectrometry. Keywords: Adsorption; Bromate; Water; Ultra-performance liquid chromatography-tandem mass spectrometry