Bene Ekine-Afolabi
University of East London, UK
Scientific Tracks Abstracts: OHDM
The oral cavity which is comprising of the dental sets, tongues, larynx and microorganisms, is an important part of the human body, food intake in healthy individual passes through the oral cavity as the first point of call. This means that every element of food has its first contact with the dental set and the mucus membrane of the oral cavity. Thus, meaning the dental set and the oral cavity will be the first home to unfriendly bacteria that are associated with food. Therefore, the initiation of immunity to unfriendly microorganisms will commence in the oral cavity. Maintaining healthy gum and teeth is a lifelong endeavor. Gum diseases and dental decay has often been treated with little or no attention to the genetic status of an individual. Glutathione is important in immune response and homeostasis of an individual, in disease prevention. Various disease including cancer, diabetes, and cardiovascular disease have been linked to poor oral hygiene; however, the implication of genetic status has not been elucidated. Accumulating evidence have shown the implication of glutathione dysfunction in diseases and shown to be common mostly in Individuals with glutathione-S-transferase polymorphisms, an enzyme responsible for the function of glutathione. Microorganisms associated to food and genetic status of glutathione S-transferase as well as glutathione availability in individuals could be the unseen team to give answer to gum disease and oral cancer prevention or treatment.
Bene Ekine-Afolabi is a graduate of River State University of Science & Technology in Applied Biology (Medical Microbiology option); with an MRes degree at University of East London, United Kingdom. She had her PhD study & worked at the Department of Natural Sciences, Middlesex University, UK. She trained in practical approach to toxicology in drug development (American College of Toxicology/British Toxicology Society). Bene Ekine-Afolabi does research in Microbiology, Molecular Biology and Cancer. Her current focus of research (which has yielded eight designed models), is on the Investigation of molecular mechanism of colorectal cancer and due to the current pandemic, has been involved in drug development for COVID-19. Bene had Harvard University part-sponsored training in therapeutic research in Cancer Biology & Therapeutic. Bene has been involved in three published peer reviewed article, two manuscript awaiting publication, among which one is on COVID-19 and was submitted to the Chief Medical Officer of United Kingdom to assist in response to the pandemic.