Rajiv Mahendru
BPS Government Medical College for Women, India
Posters & Accepted Abstracts: J Allergy Ther
Asthma is a chronic inflammatory disorder of the airways in which many cells, in particular, mast cells, eosinophils, and T lymphocytes, play a role. In susceptible individuals, this inflammation causes recurrent episodes of wheezing, breathlessness, chest tightness, and cough particularly at night and/or in the early morning. Estimated prevalence of asthma in pregnant women is 5%-9% and the prevalence appears to be increasing with 0.2% of pregnancies complicated by status asthmaticus. Pregnancy has an unpredictable effect on the underlying asthma and the scrutiny of the studies reveals that the effect depends on the severity with mild, moderate or severe forms exhibiting 13%, 26% or 50% exacerbations, respectively. Generally, unless there is a severe disease, asthma has, relatively, minor effects on pregnancy outcome. Most studies show slight increase of incidence of preeclampsia, pre-term labor, low birth weight infants and perinatal mortality. Goals of Pharmacologic Therapy revolve around Relieving bronchospasm, protecting airways from irritant stimuli and minimising pulmonary and inflammatory response to allergen exposure. Chronic Asthma Management requires the use of Beta agonists, Inhaled Corticosteroids, Theophylline and/or Leukotriene modifiers
Email: dr.rmahendru@gmail.com